Early onset neutropenia after rituximab in lupus nephritis.
نویسندگان
چکیده
E-mail: [email protected] References 1. SILVE C: Hereditary hypophosphatasia and hyperphosphatasia. Curr Opin Rheumatol 1994; 6: 3369. 2. GRAEPEL P, BENTLEY P, FRITZ H, MIYAMOTO M, SLATER SR: Reproduction toxicity studies with pamidronate. Arzneimittelforschungnn 1992; 42: 654-67. 3. BLACK AJ, TOPPING J, DURHAM B, FARQUHARSON RG, FRASER WD: A detailed assessment of alterations in bone turnover, calcium homeostasis, and bone density in normal pregnancy. J Bone Miner Res 2000; 15: 557-63. 4. PORTALE AA: Blood, calcium, phosphorus and magnesium. In FAVUS M (Ed.): Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 5th ed. Washington, USA: American Society for Bone Miner Research. 2003; p. 151-4. 5. DUNLOP DJ, SOUKOP M, McEWAN HP: Antinatal administration of aminopropylidene diphosphonate. Ann Rheum Dis 1990; 49: 955. 6. ILLDIGE TM, HUSSEY M, GODDEN CW: Malignant hypercalcemia in pregnancy and antenatal administration of intravenous pamidronate. Clin Oncol (R Coll Radiol) 1996; 8: 257-8. 7. MUNNS CF, RAUCH F, WARD L, GLORIEUX FH: Maternal and fetal outcome after long-term pamidronate treatment before conception: a report of two cases. J Bone Miner Res 2004; 19: 1742-5.
منابع مشابه
Early-Onset Neutropenia Induced by Rituximab in a Patient with Lupus Nephritis and Hemolytic Anemia
Rituximab is an anti-CD20 monoclonal antibody that has been used to treat several complications of systemic lupus erythematosus (SLE) including nephritis, cerebritis, and hematological disorders. Neutropenia is among the adverse events associated with rituximab; this usually occurs several weeks after therapy. However, early-onset neutropenia has been reported only in a few cases. Herein, we de...
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BACKGROUND AND OBJECTIVES Standard treatment for lupus nephritis, including corticosteroids and cyclophosphamide, is efficient but is still associated with refractory or relapsing disease, or severe deleterious effects. Rituximab, a monoclonal chimeric anti-B cell antibody, is increasingly used in patients with lupus nephritis, but reported series were small and had a short follow-up. DESIGN,...
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OBJECTIVE To evaluate the efficacy and safety of rituximab in a randomized, double-blind, placebo-controlled phase III trial in patients with lupus nephritis treated concomitantly with mycophenolate mofetil (MMF) and corticosteroids. METHODS Patients (n = 144) with class III or class IV lupus nephritis were randomized 1:1 to receive rituximab (1,000 mg) or placebo on days 1, 15, 168, and 182....
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عنوان ژورنال:
- Clinical and experimental rheumatology
دوره 25 2 شماره
صفحات -
تاریخ انتشار 2007